• How is sesamin synthesized from pinoresinol?
  • In sesame seeds, sesamin is synthesized from pinoresinol through the sequential formation of two methylenedioxy bridges in reactions catalysed by the P450 monooxygenase CYP81Q1 5.
  • Is pinoresinol a hypoglycemic agent in defatted sesame seeds?
  • Wikul A, Damsud T, Kataoka K, Phuwapraisirisan P. (+)-Pinoresinol is a putative hypoglycemic agent in defatted sesame ( Sesamum indicum) seeds though inhibiting ¦Á-glucosidase. Bioorg Med Chem Lett. 2012;22:5215¨C7. Kim KH, Moon E, Kim SY, Lee KR.
  • Is pinoresinol a lignan?
  • Pinoresinol is a high-value plant-derived lignan with multiple health supporting effects. Enantiomerically pure pinoresinol can be isolated from natural sources, but with low efficiency. Most chemical and biocatalytic approaches that have been described for the synthesis of pinoresinol furnish the racemic mixture.
  • Is Sesame a lignan or a tocopherol?
  • In sesame seeds, ¦Á-, ¦Ã-, and ¦Ä-tocopherols are found as tocopherol homologues. In addition to lignans and tocopherols, sesame is an important source of phytosterols, phytates, polyunsaturated fatty acids, and bioactive peptides. However, utilization potential of many of these compounds has not yet been fully understood.
  • Is sesaminol a lignan?
  • Liu, Z., Saarinen, N. M. & Thompson, L. U. Sesamin is one of the major precursors of mammalian lignans in sesame seed (Sesamum indicum) as observed in vitro and in rats. J. Nutr. 136, 906¨C912 (2006). Katayama, S. et al. Effects of sesaminol feeding on brain A¦Â accumulation in a senescence-accelerated mouse-prone 8. J. Agric.
  • Do phenolic compounds affect the bioactivity of sesame seeds?
  • Nonetheless, because sesame seeds contain a high concentration of lipid and protein fractions, interactions between phenolic compounds and proteins may affect the bioavailability and bioactivity of bioactive compounds, which displays certain limitations.